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40-Deoxy-40(S)-iodorapamycin

{Author}: Lijun Xie, Jian Zuo, Guoxin Yang, Congshen Zheng and Yuanrong Cheng*

{Journal}: Acta Crystallographica

{Year}: 2012

{Volume}:68

{Issue}:8

{Pages}: o2331

{Abstract}:The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra-molecular O-H⋯O inter-action also occurs.